Importantly, these receptors had been discovered to happen to be activated by a wide array of endogenous opioids at a focus comparable to that observed for activation and signaling of classical opiate receptors. Subsequently, these receptors were observed to acquire scavenging action, binding to and lowering endogenous amounts of opiates available
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Importantly, these receptors ended up uncovered to happen to be activated by an array of endogenous opioids at a focus much like that observed for activation and signaling of classical opiate receptors. Consequently, these receptors have been located to acquire scavenging action, binding to and reducing endogenous levels of opiates obtainable for b
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